INTELHOPE is a prospective randomized trial which is investigating the impact of radiation dose escalation to the PET defined gross disease in patients with locally advanced oropharyngeal, laryngeal and hypopharyngeal malignancies. Patients undergo PET CT prior to start of treatment which is used to define the dose escalation volume. The objectives of the study are to evaluate the toxicity with this approach and the impact on the local control.
Clinical Data Available
Clinical details of patient demographics, radiation dose, baseline PET CT information as well as response imaging and outcomes.
Imaging Available
PET CT Scan
Pretreatment Planning Image
100
Related Publications
Intensifying Radiation Treatment in Advanced/Poor Prognosis Laryngeal, Hypopharyngeal (LH), and Oropharyngeal Cancers (OPC) Using PET–CT Based Dose Escalation Strategies—INTELHOPE (Clin Trial.gov NCT02757222) Chatterjee, S. et al. International Journal of Radiation Oncology, Biology, Physics, Volume 99, Issue 2, E327 - E328
